Regulation of neuronal P53 activity by CXCR4
نویسندگان
چکیده
منابع مشابه
Regulation of neuronal P53 activity by CXCR 4.
Abnormal activation of CXCR 4 during inflammatory/infectious states may lead to neuronal dysfunction or damage. The major goal of this study was to determine the coupling of CXCR 4 to p53-dependent survival pathways in primary neurons. Neurons were stimulated with the HIV envelope protein gp120(IIIB) or the endogenous CXCR 4 agonist, SDF-1 alpha. We found that gp120 stimulates p53 activity and ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Neuroscience
سال: 2005
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2005.05.007